A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.
References
| Link | Resource |
|---|---|
| https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md | Third Party Advisory Exploit |
| https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc | Third Party Advisory Exploit |
| https://vuldb.com/?ctiid.331641 | Permissions Required VDB Entry |
| https://vuldb.com/?id.331641 | Third Party Advisory VDB Entry |
| https://vuldb.com/?submit.680872 | Third Party Advisory VDB Entry |
| https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md | Third Party Advisory Exploit |
| https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc | Third Party Advisory Exploit |
Configurations
Configuration 1 (hide)
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History
02 Dec 2025, 16:12
| Type | Values Removed | Values Added |
|---|---|---|
| References | () https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md - Third Party Advisory, Exploit | |
| References | () https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc - Third Party Advisory, Exploit | |
| References | () https://vuldb.com/?ctiid.331641 - Permissions Required, VDB Entry | |
| References | () https://vuldb.com/?id.331641 - Third Party Advisory, VDB Entry | |
| References | () https://vuldb.com/?submit.680872 - Third Party Advisory, VDB Entry | |
| First Time |
Openclinica
Openclinica openclinica |
|
| CPE | cpe:2.3:a:openclinica:openclinica:3.12.2:*:*:*:community:*:*:* cpe:2.3:a:openclinica:openclinica:3.13:*:*:*:community:*:*:* |
14 Nov 2025, 18:15
| Type | Values Removed | Values Added |
|---|---|---|
| References | () https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md - | |
| References | () https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc - |
10 Nov 2025, 00:15
| Type | Values Removed | Values Added |
|---|---|---|
| New CVE |
Information
Published : 2025-11-10 00:15
Updated : 2025-12-02 16:12
NVD link : CVE-2025-12921
Mitre link : CVE-2025-12921
CVE.ORG link : CVE-2025-12921
JSON object : View
Products Affected
openclinica
- openclinica